Tuesday, October 19, 2010

Type 2 Diabetes Mellitus Linked with Colorectal Cancer among Men

Type 2 Diabetes Mellitus is linked with increased risk of incident colorectal cancer (CRC) among men, revealed a study. The risk was higher for those participants with Type 2 Diabetes regardless of whether or not they used insulin. Though the linkage between the two conditions is evident, it is not clear if this association varies by gender or other factors.

Hyperglycemia and hyperinsulinemia, which are especially prominent during the early stages of Type 2 Diabetes, have been proposed as mediators for the association between the two diseases.

However, as far as women are concerned, the study revealed that Type 2 Diabetes and insulin use were not associated with CRC risk among them.

Peter T. Campbell, lead author of this study, said, "While our study supports an association of Type 2 Diabetes with colorectal cancer incidence among men, our results also suggest that insulin use is associated with a slight, but not a substantially increased, risk of colorectal cancer among men with Type 2 Diabetes.”

The author added, "Prevention strategies should emphasize adherence to guidelines intended for the general population such as smoking cessation, weight management, exercise and regular early detection exams.”

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